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Vince Caiozzo, PhD
Professor in Residence, Orthopaedic Surgery, UC Irvine
Director, Exercise Science Laboratory, NIH General Clinical Research Center, UC Irvine
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| Current PI funding: NIH (AR47752), Multidisciplinary Exercise Sciences Training Grant (2008-2013)
NASA (MA00403), Hypergravity Resistance Training (2004-2008) |
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| Mentoring: Dr. Caiozzo has trained 23 Doctorate and Master's level students and is PI on a T-32 training grant that provides a postdoctoral training program for individuals interested in an academic career in the field of exercise science. His trainees include Dr. Dave McAllister, Associate Professor of Orthopaedic Surgery at UCLA; and Dr. Christian Fox, Associate Clinical Professor of Emergency Medicine at UC Irvine and Director of Emergency Ultrasound. Dr. Caiozzo's teaching and mentoring excellence has been recognized by several teaching awards including the Basic Science Teaching Award in the Department of Orthopaedics at UC Irvine (2005). Dr. Caiozzo currently trains 2 post-docs. |
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| Research: The Ilizarov technique is used to lengthen long bones and salvage limb length following traumatic injuries. While previous studies have exclusively focused upon issues related to bone, very little is known about the response of skeletal muscle, connective tissue, nerve, or vessels to distraction. Dr. Caiozzo's research focuses on three key aspects of skeletal muscle: (1) the mechanistic role of contractile and regulatory proteins in muscle mechanics; (2) the mechanistic basis of muscle plasticity; and (3) the application of the first two pursuits to clinically relevant pathologies, including the development of a rodent Ilizarov model that simulates bone lengthening in humans. By developing an understanding of the adaptation of skeletal muscle to the Ilizarov technique, Dr. Caiozzo seeks to establish more optimal methods of bone lengthening. Dr. Caiozzo has published close to 100 peer-reviewed journal articles. |
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