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Dan Cooper, MD
Professor, Pediatrics, UC Irvine
Chief, Pediatric Pulmonology Division, UC Irvine
Founder and Director, Institute for Clinical and Translational Science (ICTS), UC Irvine
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| Current PI funding: NIH (R01-HL080947-15), PBMCs, exercise, and children: Initial mechanisms (2005-2010)
NIH (U01-K061259-01), Exercise strategy to prevent pediatric type 2 diabetes (2002-2009)
NIH (R01-NR009070), Assisted exercise in prematurity: Effects and mechanisms (2005-2009)
NIH (P01-HD048721), Mechanisms of health effects of exercise in children (2006-2011) |
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| Mentoring: Dr. Cooper is an exceptional mentor whose trainees have progressed to prominent national and international careers, including Dr. Ruey-Kang Chang, Associate Professor of Pediatrics and Chief of Pediatric Cardiology at Harbor-UCLA; Dr. Alon Eliakim, Professor and Chair of Pediatrics at the University of Tel Aviv School of Medicine, Israel; and Dr. Stefania Zanconato, Professor and Director of Pediatrics and Allergy at the University of Padova, Italy. Dr. Cooper has mentored 33 trainees including 3 currently. |
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| Research: Dr. Cooper is the Founding Director of the Institute for Clinical Translational Science and the Program Director of the UC Irvine Clinical Research Center. His research seeks to identify how exercise can best be used to prevent asthma and obesity in children; in particular how brief bouts of exercise alter gene expression and functional responses of neutrophils. The neutrophil is a unique cell capable of instigating disease processes such as the common exercise-induced asthma. At the same time, conditioning of neutrophils by physical activity can play a role in how exercise prevents diseases such as atherosclerosis. Dr. Cooper is particularly interested in new therapies involving both pharmacologic and lifestyle interventions. |
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